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| Author, Analytic (01) | : | Stern, Robert S. |
| Title, Analytic (04) | : | Drug promotion for an unlabeled indicationùthe case of topical tretinoin |
| Medium Designator (05) | : | Analytic survey |
| Journal Title (10) | : | New England Journal of Medicine |
| Date of Publication (20) | : | 1994 |
| Volume ID (22) | : | 4200 |
| Location in Work (25) | : | 1348-1349 |
| Notes (42) | : | Reply from: Daniel B. Stryer et al., New England Journal of Medicine 1995;332:1032; Richard S. Kalish, New England Journal of Medicine 1995;332:1032. Methodology note: Data was abstracted by a single reviewer and this may have introduced biases. A MEDLIN |
| Abstract (43) | : | Ever since the publication in 1988 of a highly controversial article on the effects of topical tretinoin (Retin-A) on the appearance of ôphotoagedö skin, Ortho Pharmaceutical, the manufacturer, has been conducting an active, controversial multimedia effort to ensure that the general public and the medical profession were aware of this ôunlabeledö indication. The author documents a dramatic increase in the prescription rates for this product since 1988 and concludes that the publicity about tretinoin has been very profitable for Ortho. |
| Keywords (45) | : | *analytic survey/United States/topical tretinoin/Retin-A/unlabeled indication/analysis of prescribing pattern/dermatology/consumer behaviour & knowledge/industry generated publicity/INFLUENCE OF PROMOTION: CONSUMERS AND PATIENTS/INFLUENCE OF PROMOTION: PRESCRIBING, DRUG USE/PROMOTION DISGUISED: PRESS CONFERENCES AND PRESS COVERAGE/PROMOTIONAL TECHNIQUES: UNLABELED INDICATIONS |
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